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Daclatasvir Prevents Hepatitis C Virus Infectivity by Blocking Transfer of the Viral Genome to Assembly Sites |
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| Authors: | Bertrand Boson Solène Denolly Fanny Turlure Christophe Chamot Marlène Dreux François-Loïc Cosset |
| Institution: | 1. CIRI - International Center for Infectiology Research, Team EVIR, Inserm, U1111, Université Claude Bernard Lyon 1, CNRS, UMR5308, Ecole Normale Supérieure de Lyon, Univ Lyon, F-69007, Lyon, France;2. Plateau Technique Imagerie/Microcopie, Lyon Bio Image, SFR-BioSciences, ENS de Lyon, Inserm US8, CNRS UMS3444, UCBL, France |
| Abstract: | |
| Keywords: | Chronic Hepatitis C Direct-Acting Antiviral Agent DAA CHX cycloheximide DCV daclatasvir DI domain I DMV double membrane vesicle ER endoplasmic reticulum HCV hepatitis C virus LD lipid droplet MOI multiplicity of infection NS non-structural protein PBS phosphate-buffered saline RC replication complex SIM structured illumination microscopy |
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