| 早期自然流产胎儿绒毛细胞培养及染色体核型分析 |
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| 引用本文： | 梁彩红,禤洁甜,汤丽霞,杨光. 早期自然流产胎儿绒毛细胞培养及染色体核型分析[J]. 广西医学, 2011, 33(6): 691-693 |
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| 作者姓名： | 梁彩红 禤洁甜 汤丽霞 杨光 |
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| 作者单位： | 广东省佛山市第一人民医院临床医学研究所,佛山市,528000 |
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| 摘 要： | 目的 探讨早期自然流的原因及流产胎儿绒毛染色体核型检查的意义.方法 应用长期培养法对60例早期自然流产的胎儿绒毛组织进行绒毛细胞培养,并对培养成功的绒毛细胞制备染色体及核型分析.结果 60例自然流产的绒毛组织中绒毛细胞培养成功56例(93.3%),56例中检出异常核型32例(57.1%),其中常染色体三体16例、多倍体...
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| 关 键 词： | 流产 绒毛细胞 染色体 核型分析 |
Chorionic Villus Cell Culture and Analysis on Chromosomal Karyotype in Early Spontaneous Abortion |
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| LIANG Cai-hong,XUAN Jie-tian,TANG Li-xia,YANG Guang. Chorionic Villus Cell Culture and Analysis on Chromosomal Karyotype in Early Spontaneous Abortion[J]. Guangxi Medical Journal, 2011, 33(6): 691-693 |
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| Authors: | LIANG Cai-hong XUAN Jie-tian TANG Li-xia YANG Guang |
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| Affiliation: | (Institute of Clinical Medicine,the First People’s Hospital of Foshan City,Guang dong,Foshan 528000,China) |
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| Abstract: | Objective To study the cause of early spontaneous abortion and the value of chromosomal karyotype analysis of the chorionic villus samples.Methods The chorionic villus specimens that were obtained through 60 cases of early spontaneous abortion were cultured for karyotype analysis.Results Of the 60 cases,chorionic villus was successfully cultured in 56 cases（93.3%）,and abnormal embryo karyotypes were identified in 32 cases（57.1%）.16 cases were antosomal triploid,6 case were multiplod,6 cases were mosaic,2 cases were sexual chromosome abnormalitie,and 2 cases were structural aberrations;normal karyotypes were identified in 24 cases（42.9%）,5 cases were males and 19 cases were females.Conclusion Embryo chromosomal abnormality is a major cause of early spontaneous abortion,and karyotype analysis of the villus helps identify the causes of abortion and ensure the success of the next pregnancy. |
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| Keywords: | Abortion Chorionic villus Chromosome Karyotype analysis |
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