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人参总皂苷对PC12细胞分化的影响
引用本文:李晗宇,王顺和,郑娟,姜蓉. 人参总皂苷对PC12细胞分化的影响[J]. 重庆医科大学学报, 2011, 36(4): 423-425
作者姓名:李晗宇  王顺和  郑娟  姜蓉
作者单位:李晗宇,王顺和,郑娟(重庆医科大学基础医学院病理学教研室);姜蓉(重庆医科大学干细胞与组织工程研究室,重庆,400016)
摘    要:目的:研究人参总皂苷(Total saponin ofpanax ginseng,TSPG)诱导PC12细胞神经元性分化的作用.方法:体外培养PC12细胞,观察PC12细胞在TSPG的影响下细胞发生的形态学改变.诱导48 h透射电镜观察突触连接形成情况,72 h利用免疫细胞化学技术,观察TSPG作用后PC12细胞向MA...

关 键 词:人参总皂苷  PC12细胞  分化

Differentiation of PC12 cells induced by total saponin of panax ginseng
LI Han-yu,et al. Differentiation of PC12 cells induced by total saponin of panax ginseng[J]. Journal of Chongqing Medical University, 2011, 36(4): 423-425
Authors:LI Han-yu  et al
Affiliation:LI Han-yu,et al(Department of Pathology,College of Basic Medicine,Chongqing Medical University)
Abstract:Objective:To study the potential ability of TSPG(Total saponin of panax ginseng)to induce the neuronal differentiation of PC12 cells.Methods:PC12 cells were cultured in vitro,and their morphological changes under the TSPG were observed.The synaptic linkage were observed by transmitting electronic microscope after the PC12 cells were exposed to TSPG for 48 h and the expression of MAP-2 was detected by immunocytochemistry after 72 h.Results:The length of neurite and max diameter of PC12 cells in TSPG group we...
Keywords:total saponin of panax ginseng  PC12 cell  differentiation  
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