A comparison of non-HDL and LDL cholesterol goal attainment in a large, multinational patient population: The Lipid Treatment Assessment Project 2 |
| |
| Authors: | Raul D Santos David D Waters Lisa Tarasenko Michael Messig J Wouter Jukema Cheng-Wen Chiang Jean Ferrieres Joanne M Foody |
| |
| Affiliation: | 1. The Lipid Clinic Heart Institute (InCor), University of São Paulo Hospital, São Paulo, Brazil;2. San Francisco General Hospital and University of California, San Francisco, CA, USA;3. Pfizer Inc., New York, NY, USA;4. Leiden University Medical Center, Leiden, The Netherlands;5. Cathay General Hospital and Taipei Medical University, Taipei, Taiwan;6. Rangueil Hospital, Toulouse, France;8. Division of Cardiovascular Medicine, Brigham and Women''s Hospital, Harvard Medical School, Boston, MA, USA |
| |
| Abstract: | ObjectiveThis study evaluated the success in attaining non-HDL-cholesterol (non-HDL-C) goals in the multinational L-TAP 2 study.Methods9955 patients ≥20 years of age with dyslipidemia on stable lipid-lowering therapy were enrolled from nine countries.ResultsSuccess rates for non-HDL-C goals were 86% in low, 70% in moderate, and 52% in high-risk patients (63% overall). In patients with triglycerides of >200 mg/dL success rates for non-HDL-C goals were 35% vs. 69% in those with ≤200 mg/dL (p < 0.0001). Among patients attaining their LDL-C goal, 18% did not attain their non-HDL-C goal. In those with coronary disease and at least two risk factors, only 34% and 30% attained respectively their non-HDL-C and LDL-C goals. Rates of failure in attaining both LDL-C and non-HDL-C goals were highest in Latin America.ConclusionsNon-HDL-C goal attainment lagged behind LDL-C goal attainment; this gap was greatest in higher-risk patients. |
| |
| Keywords: | |
| 本文献已被 ScienceDirect PubMed 等数据库收录！ |
|
