江苏省某胸部专科医院肺癌治疗的原研药与仿制药利用分析

目的：在加速仿制药替代的背景下，提出促进仿制药使用的政策建议。方法：选取江苏省某胸部专科医院治疗肺癌的8种既有原研药也有仿制药的品种，按季度分析2018年1月至2020年6月原研药和仿制药使用量占比、使用金额占比、价格比，以及2019年6月至2020年6月执行集中采购前后仿制药替代潜在的费用节省率。结果：2018年第1季度至2020年第2季度，原研药、仿制药使用数量占比分别由22.38%下降至14.26%、77.62%上升至85.87%，使用金额占比分别由39.43％下降至21.56％、60.57％上升至78.44％，仿制药与原研药价格比从2.08上升至2.75。在执行集中采购后，仿制药替代原研药潜在可节约费用1 061 254.51元，费用节省率为55.93％。结论：随着仿制药相关政策的推进，仿制药使用数量和金额占比都在上升，仿制药替代确有降低药品费用支出的作用。因此，加快仿制药一致性评价，同时配合仿制药政策的宣传，着力提高医患对仿制药的认同，再通过集中采购政策，可以促进仿制药利用以节约医疗资源。

Utilization analysis of original and generic drugs for lung cancer at a chest specialty hospital in Jiangsu Province

OBJECTIVE To provide recommendations for promoting the use of generic drugs under the background of accelerating the substitution of generic drugs. METHODS Eight kinds of drugs with both original and generic versions for non-small cell lung cancer(NSCLC)were selected from a chest specialty hospital in Jiangsu Province.The proportion of usage quantity,ratio of amount and price ratio were analyzed quarterly during January 2018-June 2020 and the potential cost-saving rates of generic drug substitution calculated before and after implementing centralized drug procurement policy during June 2019-June 2020. RESULTS From the first quarter of 2018 to the second quarter of 2020,the ratio of quantity of original drugs declined from 22.38% to 14.26% while that of generic drugs rose from 77.62% to 85.87%;the ratio of amount of original drugs decreased from 39.43% to 21.56% while that of generic drugs jumped from 60.57% to 78.44%;the price ratio of generic drug to original drug increased 2.08 to 2.75.After implementing centralized drug procurement policy,the cost of generic drugs replacing original drugs during June 2019-June 2020 could save 1 061 254.51 yuan with a cost-saving rate of 55.93%. CONCLUSION With the implementation of policies related to generic drugs,both ratio of quantity of generic drugs and ratio of amount of generic drugs has spiked.Drug expenditure may be lowered by substituting original drug with generics.For speeding up the process of conformity evaluation and cooperating with the promotion of generic drug policy,constant efforts should be made to improve physician/patient recognition of generic drugs.Adopting centralized drug procurement policy promotes the use of generic drugs to save medical expenses.