电感耦合等离子体原子发射光谱法分析珍宝类藏药七十味珍珠丸中汞的5种形态和分布

目的：研究藏药七十味珍珠丸中汞的5种存在形态和分布。方法：将七十味珍珠丸中汞的形态分为水溶态汞、溶于盐酸的无机汞和有机汞、络合汞、单质汞和残渣态汞，通过电感耦合等离子体原子发射光谱（ICP-AES）法分析5种形态汞的含量和分布。结果：藏药七十味珍珠丸中总汞的93.8%是以惰性汞形式存在的硫化汞，6.18%是与锌、铝、钙等金属氧化物形成的络合汞，0.01%是单质汞，0.04%是溶于盐酸的无机汞和有机汞，0.03%为水溶态汞。结论：通过震荡提取藏药七十味珍珠丸中不同形态汞，且5种汞形态的含量总和基本等于总汞含量。这种提取方式能够全面分析七十味珍珠丸中汞的形态，从而为控制珍宝类藏药的安全性提供了科学依据。

ICP-AES method for analyzing five species and distribution of mercury in Tibetan medicine Ranasampel

OBJECTIVE To explore the five species and distribution of mercury in Tibetan medicine Seventy Flavor Pearl Pills(RNSP). METHODS The species of mercury in RNSP were divided into water-soluble mercury,inorganic mercury and organic mercury dissolved in hydrochloric acid,complex mercury,elemental mercury and residual mercury.Then the content and distribution of five species of mercury were analyzed by Inductively Coupled Plasma-Atomic Emission Spectrometry(ICP-AES).RESULTS It was found that 93.8% of mercury in RNSP was mercury sulfide in the form of inert mercury,6.18% complex mercury formed with metal oxides such as zinc,aluminum and calcium,0.01% elemental mercury,0.04% inorganic mercury and organic mercury dissolved in hydrochloric acid and 0.03% water-soluble mercury. CONCLUSION Different mercury species in RNSP are extracted by shock and continuous chemical extraction.And the contents of five species of mercury are basically equal to the total content of mercury.This method may enable comprehensive analyses of mercury species in RNSP.Thus it provides scientific rationales for ensuring the safety of precious Tibetan medicines.