多层螺旋CT薄层靶成像技术鉴别诊断肺部磨玻璃结节的价值

目的 探讨多层螺旋CT薄层靶成像技术诊断肺部磨玻璃结节（GGN）的价值。方法回顾性分析2018年1月至2021年7月于怀来县中医医院行64排螺旋CT检查发现并经病理证实的GGN患者76例。其中良性GGN32例，恶性GGN44例。所有患者均行5 mm层厚常规螺旋CT扫描和1 mm薄层螺旋CT靶成像重建。比较良、恶性GGN影像学特征及形态特征，以及64排螺旋CT不同层厚显示效果。结果 良、恶性GGN的分叶征、空泡征、胸膜凹陷征、毛刺征及边缘欠清晰等差异均有统计学意义（P<0.05）；良、恶性GGN的形态不规则、形态规则呈圆或椭圆形、斑片状及多结节融合等差异均有统计学意义（P<0.05）。5 mm层厚常规螺旋CT扫描与1 mm薄层螺旋CT靶成像重建对GGN分叶征、空泡征、胸膜凹陷征、边缘欠清晰、毛刺征的检出率差异均有统计学意义（P<0.05）。1 mm薄层靶成像技术呈现的影像学特征明显优于5 mm层厚常规CT扫描。结论 64排螺旋CT薄层靶成像技术的应用对良、恶性GGN的鉴别诊断具有较高的临床应用价值，能明显提高早期肺癌的检出率，为临床诊疗提供参考。

Value of multislice spiral CT thin-layer target imaging in differential diagnosis of pulmonary ground glass nodules

ObjectiveTo investigate the value of thin slice CT imaging in the diagnosis of pulmonary ground glass nodules (GGN). MethodsA total of 76 patients with GGN detected by 64-slice spiral CT examination and confirmed by pathology in Huailai Hospital of Traditional Chinese Medicine from January 2018 to July 2021 were retrospectively analyzed. There were 32 cases of benign GGN and 44 cases of malignant GGN. All patients received 5 mm slice thickness conventional spiral CT scan and 1 mm thin slice spiral CT target imaging reconstruction. The imaging and morphological characteristics of benign and malignant GGN were compared, as well as the display effect of different slice thickness of 64-slice spiral CT. ResultsThere were statistically significant differences between benign and malignant GGN in lobulation sign, vacuole sign, pleural depression sign, burr sign and unclear margin (P<0.05). There were statistically significant differences between benign and malignant GGN in irregular shape, round or oval shape, patchy shape and polynodular fusion (P<0.05). Conventional spiral CT scan with 5 mm slice thickness and target imaging reconstruction with 1 mm slice spiral CT had statistically significant differences in the detection rates of GGN lobulation sign, vacuole sign, pleural depression sign, unclear edge and burr sign (P<0.05). The imaging features of 1 mm thin-slice target imaging were significantly better than conventional CT scanning with 5 mm slice thickness. ConclusionThe application of 64-slice spiral CT thin-layer target imaging technology has high clinical application value in the differential diagnosis of benign and malignant GGN, and can significantly improve the detection rate of early lung cancer, providing reference for clinical diagnosis and treatment.