2019年度广西上消化道癌机会性筛查结果分析

目的分析广西地区2019年度上消化道癌机会性筛查数据,为上消化道机会性筛查工作提供指导。方法回顾性分析从广西上消化道癌管理系统收集的2019年度(2019年7月1日—2020年6月30日)参加广西上消化道癌机会性筛查的临床病历资料。计算活检率,食管/胃肿瘤性病变检出率,食管癌/胃癌早诊率,并在不同性别组以及年龄组之间进行比较。结果共10357例受检者纳入上消化道癌机会性筛查,其中5897例进行活检组织病理学检查,食管、贲门、胃分别活检882例、178例、5392例,活检率分别为14.96%、3.02%、91.44%。共检出食管肿瘤性病变126例(1.22%),早期癌37例(29.37%);胃肿瘤性病变210例(2.03%),早期癌66例(31.43%);贲门肿瘤性病变19例(0.18%),早期癌4例(21.05%);胃及贲门肿瘤性病变229例(2.21%),胃及贲门早期癌70例(30.57%)。肿瘤性病变检出率在性别和年龄分组中比较,差异均有统计学意义(均P<0.001)。食管癌、胃癌早诊率在性别和年龄分组中比较,差异均无统计学意义(均P>0.05)。在80岁之前,食管、胃(包括贲门)肿瘤性病变的检出率均随年龄上升而上升(χ^(2)=46.716,P<0.001;χ^(2)=51.989,P<0.001)。结论2019年度广西上消化道癌机会性筛查检出率及早诊率均不高,需进一步提高人群的防癌意识,尤其是年龄≥40岁的男性人群。

Analysis of the opportunistic screening results of upper gastrointestinal cancer in Guangxi,2019

Objective To analyze the opportunistic screening data of upper gastrointestinal cancer in Guangxi in 2019 to provide guidance for the opportunistic screening of upper gastrointestinal tract. Methods The clinical medical records collected from the Guangxi upper gastrointestinal cancer management system in 2019 (July 1, 2019-June 30, 2020) for Guangxi upper gastrointestinal cancer opportunistic screening were retrospective analysis. The the biopsy rate, the detection rate of esophageal/gastric neoplastic lesions and the early diagnosis rate of esophageal cancer/gastric cancer were calculated and compared among different gender groups and age groups. Results A total of 10, 357 patients were included in the opportunistic screening of upper gastrointestinal cancer. Among them, 5, 897 patients underwent biopsy histopathological examination. The biopsy rates of esophagus, cardia and stomach were 14.96% (882 cases), 3.02% (178 cases), 91.44% (5, 392 cases), respectively. A total of 126 cases of esophageal neoplastic lesions (1.22%), 37 cases of early cancer (29.37%); 210 cases of gastric neoplastic lesions (2.03%), 66 cases of early cancer (31.43%); and 19 cases of cardia neoplastic lesions (0.18%), 4 cases of early cancer (21.05%); 229 cases (2.21%) of gastric and cardia neoplastic lesions, 70 cases (30.57%) of gastric and cardia early cancers were detected. There were statistically significant differences in the detection rate of neoplastic lesions in gender and age groups (all P<0.001). There was no significant difference in the early diagnosis rate of esophageal cancer and gastric cancer in gender and age groups (all P>0.05). Before the age of 80, the detection rate of neoplastic lesions in the esophagus and stomach (including the cardia) increased with age (χ²=46.716, P<0.001; χ²=51.989, P<0.001). Conclusions The detection rate of opportunistic screening and the rate of early diagnosis for upper gastrointestinal cancer in Guangxi in 2019 are not high. It is necessary to further improve the awareness of cancer prevention for the public, especially the male over 40 years old.