冠脉正常者双层探测器能谱CT静息态心肌灌注成像的作用

目的 探讨双层探测器能谱CT在冠脉正常者静息态心肌灌注成像的作用。 方法 对156例疑似冠心病患者行双层探测器能谱CT冠状动脉血管造影及静息态心肌灌注成像检查,对28例冠脉正常者进行静息态心肌灌注成像的测量。根据美国心脏协会 17段心脏节段分析方法,分别在碘密度图、有效原子序数图像上测量心肌各节段(心尖除外)的碘密度值及有效原子序数值,同时记录主动脉根部的碘密度值及有效原子序数值,并对所得数据进行定量分析。 结果 左室中部层面各节段的碘密度值及有效原子序数差异有统计学意义(P均<0.001),基底部层面及心尖部层面心肌各节段的碘密度值及有效原子序数差异无统计学意义(P均>0.05)。结论 双层探测器能谱CT可以定量分析心肌各节段的碘浓度和有效原子序数,冠脉正常者左心室中部层面各节段的灌注不同。

Role of Dual-layer Detector Energy Spectral CT in Resting Myocardial Perfusion Imaging for Patients with Normal Coronary Artery

Objective To investigate the role of dual-layer detector energy spectral CT in resting myocardial perfusion imaging for patients with normal coronary artery. Methods One hundred and fifty-six patients with suspected coronary heart disease underwent dual-layer detector energy spectral CT coronary angiography,and resting myocardial perfusion imaging was performed for 28 patients with normal coronary artery.According to American Heart Association’s 17-segmentmodel,the iodine density and effective atomic number(Z_eff value)of each myocardial segment(except for apical segment)were measured and normalized to those of the aorta.All the data were quantitatively evaluated using ANOVA or Friedman test. Results Iodine density and Z_eff value of myocardial segments in middle plane were significantly different(all P<0.001).The iodine density and Z_eff value showed no significant difference between segments in basal and apical plane(all P > 0.05). Conclusions Iodine density and Z_eff value of myocardial segments can be quantitatively evaluated using dual-layer detector energy spectral CT.Resting myocardial perfusion of segments in middle plane are significantly different in patients with normal coronary artery.