冠心病人患胆结石危险因素的非条件Logistic回归分析

对260例冠心病人有否胆结石者进行成组匹配病例对照研究。非条件 Logistic 回归分析结果表明:初筛出的11项阳性变量经多因素分析,最终被入选的8项阳性变量中胃切除、慢性肠道疾患、慢性胆囊炎、糖尿病、肝硬化、安妥明及干性饮食习惯七项阳性变量,可能是本次调查冠心病人患胆结石的主要危险因素,具比值比(OR)分别为4.08、9.36、4.10、2.67、5.82、3.82、1.72,饮水可能是保护因素,其比值比为0.27。而高血清脂质水平、过度肥胖及摄入高胆固醇和高脂肪等因素,两组均无统计学差异(P>0.05)。说明脂质代谢失调与胆结石无直接联系。

Non-Conditional Logistic Regression Analysis of Risk Factors about the Coronary Heart Patients with Gallstones

In order to find out major risk factors about the coronary heart patients with gallstones,a case-control study of 130 cases and 130 controls were carried out in Nanjing 1990.Multivariate non-conditional logistic regression analysis of 11 variables showed that the following 8 risk factors were related with gallstones of the corroray heart patients,i,e.gastrectomy,chronic intestinal diseases,previous cholecystitis,diabetes,cirrhosis,clofibrate,dry diet,drinking water.The odds ratios(OR)were 4.08,9.36,4.10,2.67,5.82, 3.82,1.72,0.27,respectively.There was no difference in the positive rate of high serious lipid level,obesity,high cholesterol and fat intake between cases and controls.It is demonstrated that the imbalance of lipid metabolism had no direct relationship with gallstones.