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高血压患者血压参数与颈动脉粥样硬化的相关研究
引用本文:李亚楠,布娃加·吾守尔,木尼热·马合苏提.高血压患者血压参数与颈动脉粥样硬化的相关研究[J].心血管康复医学杂志,2014,23(6):623-626.
作者姓名:李亚楠  布娃加·吾守尔  木尼热·马合苏提
作者单位:1. 新疆医科大学第一附属医院干部病房内二科,新疆乌鲁木齐,830054
2. 新疆医科大学第一附属医院医学检验中心,新疆乌鲁木齐,830054
摘    要:目的:探讨高血压患者不同血压参数与颈动脉粥样硬化的相关性.方法:选择我院2011年6月~2013年5月符合入选标准的143例高血压患者,经诊室血压、动态血压监测(ABPM)、颈动脉超声及血生化检测.根据颈动脉内膜中层厚度,患者被分为颈动脉硬化(CAS)组(106例)和无CAS组(37例).结果:(1)与无CAS组比较,CAS组的诊室收缩压(120.16±11.53) mmHg比(133.15±16.81) mmHg],24h平均收缩压24hSBP,(119.78±11.67) mmHg比(132.87±16.63) mmHg]、脉压24hPP,(48.60±8.12) mmHg比(59.51±15.32)mmHg],白天平均收缩压dSBP,(121.57±11.78) mmHg比(134.15±16.86) mmHg]、脉压dPP,(48.65±8.45) mmHg比(58.72±14.06) mmHg],夜间平均收缩压nSBP,(114.22±13.49) mmHg比(130.54±18.70)mmHg]、舒张压nDBP,(66.81±10.41) mmHg比(71.40±12.53) mmHg]、脉压nPP,(47.86±9.21) mm-Hg比(59.82±15.61) mmHg]明显升高(P<0.05);(2)偏相关性分析显示颈动脉内膜至中膜厚度(CA-IMT)值与诊室收缩压、24hSBP、24hPP,dSBP、dPP,nSBP、nDBP、nPP呈正相关(r=0.48~0.70,P<0.05).结论:高血压患者多种血压参数与颈动脉粥样硬化有显著的相关性.

关 键 词:高血压  血压测定  颈动脉疾病

Correlation among blood pressure parameters and carotid atherosclerosis in patients with essential hypertension
LI Ya-nan,Buwajia WUSHOUER,Munire MAHESUTI.Correlation among blood pressure parameters and carotid atherosclerosis in patients with essential hypertension[J].Chinese Journal of Cardiovascular Rehabilitation Medicine,2014,23(6):623-626.
Authors:LI Ya-nan  Buwajia WUSHOUER  Munire MAHESUTI
Institution:LI Ya-nan, Buwajia WUSHOUER, Munire MAHESUTI(Second Department of Internal Medicine, Cadres Ward, First Affiliated ltospital of Xinjiang Medical University, Urumqi, Xinjiang, 830054, China)
Abstract:Objective: To investigate the correlation among blood pressure parameters and carotid atherosclerosis (CAS) in patients with essential hypertension (EH). Methods: A total of 143 EH patients who met the enrollment criteria from Jun 2011 to May 2013 in our hospital were selected. Patients received measurements of office blood pressure, ambulatory blood pressure monitoring (ABPM), carotid ultrasound and blood biochemical indexes. According to carotid intima-media thickness (IMT), they were divided into CAS group (n = 106) and non-CAS group (n= 37). Results: (1) Compared with non-CAS group, there were significant rise in office systolic blood pressure (SBP) ~ (120.16 ± 11.53) mmHg vs. (133.15 ± 16.81) mmHg], 24h mean SBP 24hSBP, (119.78 ± 11.67) mmHg vs. (132.87 ± 16.63) mmHg], 24h mean pulse pressure 24hPP, (48.60 ± 8.12) mmHg vs. (59.51 ± 15.32) mm- Hg], daytime mean SBP dSBP, (121.57 ± 11.78) mmHg vs. (134.15 ± 16.86) mmHg], daytime mean PP dPP, (48.65 ± 8.45) mmHg vs. (58.72 ± 14.06) mmHg], nighttime mean SBP EnSBP, (114.22 ± 13.49) mmHg vs. (130.54_± 18.70) mmHg], nighttime mean diastolic blood pressure nDBP, (66.81 ± 10.41) mmHg vs. (71.40 ± 12.53) mmHg] and nighttime mean PP EnPP, (47. 86 ± 9.21) mmHg vs. (59. 82 ± 15. 61) mmHg] in CAS group, P〈 0. 05 all partial correlation analysis indicated that carotid IMT was positively correlated with office SBP, 24hSBP, 24hPP, dSBP, dPP, nSBP, nDBP and nPP (r = 0.48-0.70, P〈0.05). Conclusion: There are significant correlations among mul- tiple blood pressure parameters and carotid atherosclerosis in patients with essential hypertension.
Keywords:Hypertension  Blood pressure determination  Carotid artery diseases
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