葛根素复合星状神经节阻滞治疗突发性耳聋疗效观察

目的:观察葛根素复合星状神经节阻滞治疗突发性耳聋的疗效。方法:突发性耳聋患者75例,随机分为3组:葛根素组(A组)采用葛根素治疗,每次200~400mg静脉滴注,每日1次,10次为1个疗程;星状神经节阻滞组(B组)以1%利多卡因10mL加维生素B12 500μg,行星状神经节阻滞(双侧者交替阻滞),1次/d,连续10d为1个疗程;C组使用A组和B组2种方法联合治疗。每组各25例,观察治疗效果及不良反应。结果:3组病例治疗后耳聋症状均有改善,A组有效率为64%,B组有效率为80%,C组有效率为92%;与A组、B组相比较,C组痊愈率和有效率显著提高(P <0.05或P <0.01)。结论:葛根素复合星状神经节阻滞治疗突发性耳聋的疗效令人满意,值得推广应用。

Therapeutic Efficacy of Combination of Puerarin and Stellate Ganglion Block on Sudden Deafness

Objective: To observe the therapeutic efficacy of combination of Puerarin and Stellate Ganglion Block on Sudden Deafness. Methods: 75 cases were randomly divided into three groups, there were 25 cases in every groups respectively. In group A, Puerarin was used and group B was treated with Stellate Ganglion Block(SGB). In group C, both Puerarin and SGB were used. The therapeutic efficacy and side effects were recorded. Results: The effective rate of group A was 64%, group B was 80% and group C was 92%. Group C was more effective than the group A and group B in increasing the total effective rate of sudden deafness (P <0.05 or P <0.01). Conclusion: Combination of Puerarin and SGB was an effective way for the therapy of patients with sudden deafness. It can increase the total effective rate of sudden deafness.