超声组织定征对顿抑心肌各层损伤程度的实验研究

目的：探讨超声组织定征对顿抑心肌各层损伤程度的意义。方法：使用HP 5500型彩超仪及S8探头，各项设置在试验中保持一致，犬13条，麻醉后开胸，结扎冠状动脉左前降支近端，15min后再灌注，检测基础状态。结扎 15min，再灌注后心内，外膜下心肌的背向散射积分周期变化幅芳和室壁增厚率的变化。结果：结扎15min后，周期变化幅度均减少或消失，尤以心内膜下心肌为显著，室壁增厚率明显降低；再灌注后，心外膜下心肌的周期变化幅度恢复最快，心仙膜下心肌次之，室壁增厚率最慢，结论：顿抑心肌各层的损伤程度不一样，心内膜下心肌损伤较重。

Experimental study on transmural injury degree of stunned myocardium by ultrasonic integrated backscatter tissue characterization

Objective To understand the transmural injury degree of stunned myocardium by ultrasonic integrated backscatter tissue characterization.Methods The left anterior descending coronary of 13 anaesthesia open-chest dogs were ligated and released after 15 minutes and the subepicardial,subendocardical cyclic variation of integrated backscatter(CVIB) and wall thickening (WT) of basic state were measured during 15 minutes after ligation and reperfusion by HP Sonos 5500 with S8 transducer.Results After 15 minutes ligation,CVIB was blunted or decreased,WT was decreased dramatically (P< 0.01 ). After reperfusion,subepicardial CVIB was the first one returned to normal value,the second was subendocardical CVIB,and WT was the last.Conclusions The transmural injury degree in stunned myocardium was different,the subendocardical myocardium was more serious.