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Migraine without aura: genome-wide association analysis identifies several novel susceptibility
Authors:De Vries,B Loci,Freilinger, T,Anttila, V,Malik, R,Terwindt, GM,Pozo-Rosich,P,Winsvold,B,Nyholt,D,van Oosterhout,WPJ,Artto,V,Todt,M,Hä      inen,E,Fernandez-Moralez,J,Louter,M,Kaunisto,MA,Schoenen,J,Raitakari,O,Lehtimä  ki,T,Ville-Pueyo,M,Gö  bel,H,Wichman,E,Sintas,C,Uitterlinden,A,Hofman,A,Rivadeneira,F,Heinze,A,Tronvik,E,van Duin,CM,Kaprio,J,Cormand,B,Wessman,M,Frants,RR,Meitinger,T,Mü  ller-Myhsok,B,Zwart,JA,Fä  rkkilä  , M,Macaya, A,Ferrari, MD,Kubisch, C,Palotie, A,Dichgans, M,van den Maagdenberg,AMJ
Affiliation:1. Department of Neuroscience, Norwegian University of Science and Technology, Trondheim, Norway
2. Michigan State University, East Lansing, Michigan, USA
3. Chikankata Health Services, Mazabuka, Michigan, Zambia
Abstract:

We discuss the comments on our article “Sleep quality, arousal and pain thresholds in migraineurs. A blinded controlled polysomnographic study” published in JHP 2013 Feb 14;14(1):12. We hypothesize that migraineurs need more sleep than healthy controls and more sleep than they manage to achieve. Some migraineurs probably have a decreased ability to process incoming stimuli. Increased spontaneous pain may follow either sleep restriction or sleep disturbance. A comparison of migraineurs with attack onset related to sleep, migraineurs with attack onset not related to sleep and controls will be reported in another paper.

Keywords:
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