重症脑梗死脑血流动力学的动态观察

目的:动态观察重症脑梗死脑血流动力学变化的特征和规律。方法:对42例急性重症脑梗死患者进行连续7天的TCD检测,20例正常人TCD检测数据作为正常组。结果:急性重症脑梗死患者脑血流速度减慢。血管阻力参数值(Pl、Rl)增大,病程的3～5天各指标变化达高峰。结论:根据脑血流动力学的特征性改变,表明重症脑梗死在病程早期就有不同程度的缺血性脑水肿发生,进展迅速,多在病程的3—5天达高峰:TCD用于床旁连续监测,可通过动态观察TCD参数变化,评价颅内压变化、判断预后。

The cerebral hemodynamic change of severe acute cerebral infarction

Objective; To study the characteristic changes ofcerebral hemodynamic in patients with severe acute cerebral, mfarction. Methods; 42 patients with severeacute cerebral-infarction were examimed withTCD every day. 20normal as central were examined withTCD too. Results; In patients with severe acute cerebral infarction, the cerebralblood flow velocity ( V, Vm ) decreased and the parameter of cerebral vessels resistance(PI,RI) increased. The markers peak appear during 3 -5 days. Conclusion ; Based on the characteristic change of cerebral hemodynamic obtained by TCD, progress of ischemic brain edema is characteristic . The various level alteration of brain water content was present at earlier progress and progress qmcrly. The peak occur during 3-5 day. Noninvasive TCD may provjde the important evidence for dyhamicai observation of increased ICP and assess treatment effect;We could judge prognosis through continuously monitoring intracranial pressure using TCD.