| 急性白血病患者血清可溶性白细胞介素2受体水平测定 |
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| 引用本文： | 王丽峰,孙秉中,范玉红,于文斌.急性白血病患者血清可溶性白细胞介素2受体水平测定[J].白血病．淋巴瘤,1996(2). |
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| 作者姓名： | 王丽峰 孙秉中 范玉红 于文斌 |
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| 作者单位： | 解放军四六四医院，第四军医大学西京医院 |
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| 摘 要： | 用双抗体夹心酶联免疫吸附试验检测５６例急性白血病（ＡＬ）患者血清可溶性白细胞介素２受体（ＳＩＬ－２Ｒ）水平。结果显示：ＡＬ初诊患者血清ｓＩＬ－２Ｒ水平显著高于正常对照，正常对照与完全缓解者之间无显著差异；不同类型ＡＬ患者血清ｓＩＬ－２Ｒ水平间无显著差异。急性白血病ｓＩＬ－２Ｒ水平与骨髓中白血病细胞百分数间有明显的相关性。血清ｓＩＬ－２Ｒ水平可作为ＡＬ病情监测、疗效观察及预后判断的有用指标之一。
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| 关 键 词： | 可溶性白细胞介素2受体 急性白血病 |
THE MEASUREMENT OF SERUM LEVELS OF SOLUBLE INTERLEUKIN-2 RECEPTOR IN PATIENTS WITH ACUTE LEUKEMIA |
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| Wang Lifeng,Sun Bingzhong, Fan Yuhong , et al.THE MEASUREMENT OF SERUM LEVELS OF SOLUBLE INTERLEUKIN-2 RECEPTOR IN PATIENTS WITH ACUTE LEUKEMIA[J].Journal of Leukemia & Lymphoma,1996(2). |
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| Authors: | Wang Lifeng Sun Bingzhong Fan Yuhong |
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| Abstract: | Serum leve of soluble interleukin-2 receptor sIL-2R were determined withELISA in 56 patients with acute leukemia. The results showed that serum levels of sIL-2R innewly diagnosed patients with acute leukemia were significantly higher than those of normalcontrols. There was no marked differences in sIL-2R levels between patients of completerenission and normal controls, and no significant difference in sIL-2R levels among patients withdifferent types of acute leukemia. The levels of sIL-2R was markedly correlated with thepercentage of leukemic cells in bone marrow. The clinical significance of serum sIL-2R levels inpatients with acute leukemia and the mechanism involved were also discussed. |
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| Keywords: | Soluble interleukin-2 receptor Acute leukemia |
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