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Follicular malignant non-Hodgkin's lymphoma with pronounced plasmacytic differentiation: A plasmacytoma-like lymphoma
Authors:U. Schmid  J. Karow  K. Lennert
Affiliation:(1) Institut für Pathologie, Kantonsspital, CH-9007 St. Gallen, Switzerland;(2) Abteilung für Hämatologie und Onkologie, Universitätsklinikum Steglitz, Hindenburgdamm 30, D-1000 Berlin 45;(3) Institut für Pathologie, Klinikum der Christian-Albrechts-Universität, Hospitalstrasse 42, D-2300 Kiel, Federal Republic of Germany
Abstract:Summary A case of follicular centroblastic-centrocytic lymphoma with an unusually pronounced plasmacytic component occurring in the gingiva and cervical lymph nodes of a 74-year-old male patient is described. Immunohistological analysis revealed a monotypic intracytoplasmic immunoglobulin pattern (IgM/lambda). The relation between follicular malignant non-Hodgkin's lymphomas and extramedullary plasmacytome is discussed. In the present case the tumour may represent the development of an autonomous plasma cell clone within a follicular centroblastic-centrocytic lymphoma.Dedicated to Professor Dr. F. Gloor, St. Gallen, on the occasion of his 60th birthday
Keywords:Follicular non-Hodgkin's lymphoma  Centroblastic-centrocytic lymphoma  Non-Hodgkin's lymphoma with plasmacytic component  Plasma cell differentiation  Extramedullary plasmacytoma
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