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淋巴结核丸对H37Rv、耐多药结核菌体外药敏实验研究
引用本文:李建国,高爱社,刘湘花,李宁宁. 淋巴结核丸对H37Rv、耐多药结核菌体外药敏实验研究[J]. 河南中医药学刊, 2008, 0(3): 20-21
作者姓名:李建国  高爱社  刘湘花  李宁宁
作者单位:河南中医学院基础医学院,河南郑州450008
基金项目:河南省科技厅重点科研项目(编号:940407058)
摘    要:目的:淋巴结核丸对强毒人型结核菌(H37Rv)及耐多药结核菌(mutiple drugs resistant Bacillus tuberculosis,MDR-TB)在体外药敏实验。方法:用美国B-D公司生产试剂12B培养液和Bectec-460检测仪检测。结果:实验表明淋巴结核丸对H37Rv具有抑制作用,最低抑菌浓度为22.5mg/ml;对MDR-TB具有显著的抗菌作用P〈0.01,最低抗菌浓度为22.5mg/ml,而对照药异烟肼、利福平、乙胺丁醇无抑菌作用。结论:用淋巴结核丸对H37Rv、MDR-TB均具有抑菌作用。

关 键 词:淋巴结核丸  结核分枝杆菌  H37RV  MDR-TB  药敏实验

The Effect of Crewels Pills on H37Rv and MDR- TB in vitro
Li Jianguo,Gao Aishe,Liu Xianghua,Li Ningning. The Effect of Crewels Pills on H37Rv and MDR- TB in vitro[J]. Journal of Henan college of Traditional Chinese Medicine, 2008, 0(3): 20-21
Authors:Li Jianguo  Gao Aishe  Liu Xianghua  Li Ningning
Affiliation:(Henan College of Chinese Medicine, Zhengzhou, Henan, China, 450008)
Abstract:Objective: to observe the effect of crewels pills on H37Rv and MDR - TB in vitro. Method: the 12B culture fluid and Bectec - 460 detection was used in experiment. Result: crewels pills have the depressant effect to H37Rv and antibacterial action to MDR - TB. The minimal inhibitory concentration is 22.5 mg/ml. The arrnazide, rifadin and etbarnbutol have not the hacteriostatic action. Conclusion: the rewels pills have bacteriostatic action to H37Rv and MDR - TB.
Keywords:crewels pills  mycobacterium tuberculosis  H37Rv  MDR- TB  drug sensitive experiment
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