小肠间质瘤的诊治

目的 探讨小肠间质瘤的诊断和治疗方法.方法 回顾性分析32例空回肠间质瘤患者的临床资料.结果 32例患者平均发病年龄52.8岁,病程10h至5年.主要临床表现为黑便、腹痛、腹部肿块、腹胀不适、发热、乏力、贫血、体重下降等.发生部位:窄肠26例,回肠5例,空回肠多原发性1例.B超检查12例提示腹腔肿块,其中4例提示来源于肠道,5例小能提示来源,3例误诊为卵巢肿瘤.4例行消化道造影,均阴性.20例行CT检查,均发现肿瘤或转移病灶,阳性发现率100%,其中15例定位于肠道肿瘤(75.0%).8例行数字减影血管造影(DSA),6例提爪小肠肿瘤.5例行小肠镜检查,均明确诊断小肠肿瘤.所有患者均手术治疗.术后经病理及免疫组化证实为间质瘤.4例肝转移患者口服格列卫治疗.22例获得0.5～5年的随访,术后复发4例,肝转移2例,死亡2例.结论 空回肠间质瘤缺乏特征性临床表现,CT和DSA对诊断有帮助,小肠镜诊断率高,手术及分子靶向治疗是其有效治疗方式.

The diagnoses and treatment of small intestinal stromal tumor

Objective To study the diagnosis and treatment of small intestinal stromal tumor(SIST).Methods We retrospectively analysed the clinical information of 32 patients with SIST.Results The average onset age of the patients was 52.8 years.The main clinical manifestations were dark stools,abdominal pain,abdominal mass,abdominal distention,fever,debilitation,anaemia,and loss of body weight.The tumors were located in jejunum in 26 cases,in ileum in 5 cases,and 1 patient had multiple tumors in both jejunum and ileum...