Cytotoxic triterpenoids from Maytenus retusa |
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| Authors: | Oramas-Royo Sandra M Chávez Haydee Martín-Rodíguez Patricia Fernández-Pérez Leandro Ravelo Angel G Estévez-Braun Ana |
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| Affiliation: | Instituto Universitario de Bio-Orga?nica Antonio González, Avenida Astrofi?sico Francisco Sánchez 2, La Laguna, Tenerife, Spain. |
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| Abstract: | Seven new triterpenoids (1-7) and 36 known compounds were isolated from the root bark of Maytenus retusa. Their structures were determined by 1D and 2D spectroscopic studies. Several compounds were evaluated for their cytotoxicity against the human tumor cell lines HL-60 and MCF-7. Some of them were cytotoxic, with IC(50) values ranging between 0.2 and 4.7 μM. |
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