全身骨显像结合局部SPECT/CT在诊断椎体良恶骨折中的价值

目的探讨全身骨显像结合局部SPECT/CT在诊断椎体良恶骨折中的价值。方法回顾分析经过病理或临床证实的52例椎体骨折患者的骨扫描及SPECT/CT资料,比较良性组与恶性组间的差异。结果骨扫描发现78.8%(41/52)的患者伴有椎体外病灶,但良性组出现病灶的人数明显少于恶性组;SPECT/CT发现恶性组椎体出现骨质破坏及椎弓根异常浓聚的人数明显高于良性组;对于结核及甲旁亢患者骨扫描及SPECT/CT缺乏特异表现。结论虽然骨扫描及SPECT/CT仍存在一定局限性,但两者结合可以充分发挥各自优势,非常适合脊柱骨折病人的筛查及良恶性鉴别。

The Value of Whole-body Bone Scan Combined with SPECT/CT in Diagnosing Benign and Malignant Vertebral Fractures

Objective To evaluate the value of whole-body bone scan （WBS） combined with SPECT/CT in di- agnosing of benign and malignant vertebral fractures. Methods WBS and SPECT/CT data of 52 cases with vertebral fractures were reviewed and analyzed retrospectively, and the differences between the benign and ma- lignant vertebral fractures were compared. Results WBS found 78.8% （41/52）patients had lesions in the bones besides the spine, but the benign group was less in number. SPECT/CT found that malignant group was more likely to have bone destructions or pedicle radionuclide uptake than the benign group. Both of them had no radioactivity concentration in the tuberculosis or hyperparathyroidism. Conclusion Although it still had some limitations, WBS combined with SPECT/CT is valuable in the diagnosis of benign and malignant vertebral frac- tures.