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白藜芦醇在眼眶淋巴瘤中应用的展望
引用本文:何广辉,孙丰源,唐东润. 白藜芦醇在眼眶淋巴瘤中应用的展望[J]. 眼科研究, 2007, 25(2): 153-156
作者姓名:何广辉  孙丰源  唐东润
作者单位:300020,天津市眼科医院眼眶整形科
摘    要:白藜芦醇是一种从植物中提取出来的生物防御素。近年来,有关细胞实验研究证实,白藜芦醇具有抗肿瘤作用。其抗肿瘤作用主要是通过防止正常细胞恶变为肿瘤细胞、抑制肿瘤细胞增生、促进肿瘤细胞凋亡来实现。大多数的眼眶淋巴瘤在病理学上表现为B细胞淋巴瘤。目前临床上其治疗方法没有一个公认的模式。随着天然生物提取剂在一些肿瘤化疗中的应用以及取得的较好疗效,将白藜芦醇引入眼眶淋巴瘤的化疗将会丰富眼眶淋巴瘤的治疗手段,并很有可能取得更好的治疗效果。就白藜芦醇在眼眶淋巴瘤中应用的展望做一综述。

关 键 词:白藜芦醇  抗肿瘤  眼眶淋巴瘤
文章编号:1003-0808(2007)02-0153-04
修稿时间:2006-08-202006-11-03

Prospect for the utilization of resveratrol in orbital lymphoma
He Guanghui.. Prospect for the utilization of resveratrol in orbital lymphoma[J]. Chinese Ophthalmic Research, 2007, 25(2): 153-156
Authors:He Guanghui.
Affiliation:Tianjin Eye Hospital, Tianjin 300020, China
Abstract:Resveratrol is a kind of phylaxin which is found in relatively high concentrations in grape berry skins.Recent researches indicated that resveratrol strongly inhabits the formation of tumor by three routes:preventing normal cells from turning into tumor cells,suppressing the proliferation of tumor and inducing apoptosis of tumor cells.It is worthy that resveratrol can obviously mediate apoptosis of B lymphoma cells.The majority of orbital lymphoma belongs to B cell lymphoma.There is not a effective approach to the management of orbital lymphoma.In modern clinical therapy of tumor,more and more natural phylaxin are utilized,and show a really good effectiveness in clinic.It is probably that resveratrol will be concerned as a natural anti-tumor agent and show a potential prospect in the chemotherapy of orbital lymphoma.
Keywords:resveratrol    antitumor   orbital lymphoma
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