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Total ocular, anterior corneal and lenticular higher order aberrations in hyperopic, myopic and emmetropic eyes
Authors:Philip Krupa  Martinez Aldo  Ho Arthur  Conrad Fabian  Ale Jit  Mitchell Paul  Sankaridurg Padmaja
Institution:a Brien Holden Vision Institute, Sydney, Australia
b School of Optometry and Vision Science, The University of New South Wales, Sydney, Australia
c The Vision Cooperative Research Center, Sydney, Australia
d Center for Vision Research, Department of Ophthalmology, Sydney, Australia
e Westmead Millennium Institute, University of Sydney, Sydney, Australia
f Asia Center of Excellence, ALCON Laboratories, Pasir Panjang Road, Mappletree Business City, Singapore
g Moreton Eye Group, Redcliffe, Queensland, Australia
Abstract:Total ocular higher order aberrations and corneal topography of myopic, emmetropic and hyperopic eyes of 675 adolescents (16.9 ± 0.7 years) were measured after cycloplegia using COAS aberrometer and Medmont videokeratoscope. Corneal higher order aberrations were computed from the corneal topography maps and lenticular (internal) higher order aberrations derived by subtraction of corneal aberrations from total ocular aberrations. Aberrations were measured for a pupil diameter of 5 mm. Multivariate analysis of variance followed by multiple regression analysis found significant difference in the fourth order aberrations (SA RMS, primary spherical aberration coefficient) between the refractive error groups. Hyperopic eyes (+0.083 ± 0.05 μm) had more positive total ocular primary spherical aberration compared to emmetropic (+0.036 ± 0.04 μm) and myopic eyes (low myopia = +0.038 ± 0.05 μm, moderate myopia = +0.026 ± 0.06 μm) (< 0.05). No difference was observed for the anterior corneal spherical aberration. Significantly less negative lenticular spherical aberration was observed for the hyperopic eyes (−0.038 ± 0.05 μm) than myopic (low myopia = −0.088 ± 0.04 μm, moderate myopia = −0.095 ± 0.05 μm) and emmetropic eyes (−0.081 ± 0.04 μm) (< 0.05). These findings suggest the existence of differences in the characteristics of the crystalline lens (asphericity, curvature and gradient refractive index) of hyperopic eyes versus other eyes.
Keywords:Total ocular aberrations  Corneal aberrations  Lenticular aberrations  VOL-CT  Primary spherical aberration
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