| 中医解毒法治疗慢性萎缩性胃炎癌前病变的实验研究进展 |
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| 引用本文： | 刘冬梅,房墅,张新,王瑞. 中医解毒法治疗慢性萎缩性胃炎癌前病变的实验研究进展[J]. 上海中医药杂志, 2016, 50(9): 101-103 |
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| 作者姓名： | 刘冬梅 房墅 张新 王瑞 |
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| 作者单位： | 山东中医药大学附属医院消化科,山东济南,250012,山东中医药大学2014级研究生,山东济南,250014,山东中医药大学附属医院消化科,山东济南,250012,山东中医药大学附属医院消化科,山东济南,250012 |
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| 基金项目： | 山东省重点研发计划项目(2015GSF119009) |
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| 摘 要： | 综述近年中医药从毒论治萎缩性胃炎癌前病变的实验研究进展。“毒邪”是慢性萎缩性胃炎(CAG)癌前病变发生发展的重要病因,解毒是阻断甚或逆转慢性萎缩性胃炎癌前病变进展的重要治法。从对胃黏膜损伤后修复的干预,对胃肠激素的调节,对自由基代谢的影响及对癌基因表达的影响、细胞增殖与凋亡的调控等方面,总结分析中医药从毒论治萎缩性胃炎癌前病变的实验研究进展。
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| 关 键 词： | 慢性萎缩性胃炎 癌前病变 解毒 中医药治疗 实验研究 综述 |
| 收稿时间： | 2016-01-20 |
Experimental research progress on detoxification method of traditional Chinese medicine in the treatment of precancerous lesions of chronic atrophic gastritis |
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| LIU Dong-mei,FANG Shu,ZHANG Xin and WANG Rui. Experimental research progress on detoxification method of traditional Chinese medicine in the treatment of precancerous lesions of chronic atrophic gastritis[J]. Shanghai Journal of Traditional Chinese Medicine, 2016, 50(9): 101-103 |
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| Authors: | LIU Dong-mei FANG Shu ZHANG Xin WANG Rui |
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| Affiliation: | Department of Digestive Diseases,Hospital Affiliated to Shandong University of Traditional Chinese Medicine,Jinan,250012,Shandong University of Traditional Chinese Medicine,Jinan,250014,Department of Digestive Diseases,Hospital Affiliated to Shandong University of Traditional Chinese Medicine,Jinan,250012 and Department of Digestive Diseases,Hospital Affiliated to Shandong University of Traditional Chinese Medicine,Jinan,250012 |
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| Abstract: | This article reviewed the experimental research progress on traditional Chinese medicine in the diagnose and treatment of precancerous lesions of chronic atrophic gastritis based on toxin in recent years. Considering toxin as important factor of precancerous lesions of chronic atrophic gastritis(CAG),detoxification is important therapy for the block or even reverse precancerous lesions of CAG. The experimental research progress on traditional Chinese medicine in the treatment of precancerous lesions of CAG based on toxin were analyzed and summarized from the following aspects:intervention on injury repair of gastric mucosal, regulation of gastrointestinal hormones, effect on free radical metabolism and cancer gene expression, regulation of cell proliferation and apoptosis. |
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| Keywords: | chronic atrophic gastritis precancerous lesions detoxification therapy of traditional Chinese medicine experimental study review |
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