甘肃陇南地区农村人群不同性别甲状腺结节患病状况调查

［摘要］ 目的 调查甘肃陇南地区农村人群甲状腺结节患病率及不同情况下甲状腺结节检出率的差异。 方法 采用分层整群抽样方法对甘肃陇南地区进行横断面调查研究，分析不同性别、年龄、甲状腺功能组中甲状腺结节的检出率，并采用Logistic回归分析甲状腺结节的危险因素。 结果 甘肃陇南地区1 289例受检者中共检出甲状腺结节214例，总体患病率为16.60%（214/1 289），男性和女性患病率分别为13.04%(84/644)、20.16%(130/645)，女性患病率明显高于男性（P＜0.05）；随着年龄增长，男性和女性甲状腺结节的患病率逐渐增加（P＜0.05）,且≥60岁组女性患病率明显高于男性（P＜0.05）。在男性和女性中，甲状腺功能异常组中结节的检出率均明显高于甲状腺功能正常组（P＜0.05）。Logistic回归分析结果显示，年龄≥60岁和吸烟为甲状腺结节的危险因素（P＜0.05）。 结论 甘肃陇南地区女性甲状腺结节检出率高于男性，且随着年龄增长逐渐增加；甲状腺功能异常可能会影响甲状腺结节的发生。

Survey on the prevalence of thyroid nodules among different sexes in rural population in Longnan area of Gansu

〗［Abstract］ Objective To investigate the prevalence of thyroid nodules in rural population in Longnan area of Gansu. Methods A stratified cluster sampling method was used to conduct a cross-sectional survey of the area. We analyzed the detection rate of thyroid nodules in different gender, age, and thyroid function groups, and used Logistic regression to analyze the risk factors of thyroid nodules. Results A total of 214 thyroid nodules were detected in 1 289 subjects in Longnan, Gansu. The overall prevalence was 16.60%(214/1 289), and the prevalence of male and female were 13.04%(84/644) and 20.16%(130/645), and the prevalence of female significantly higher than male, the difference was statistically significant(P＜0.05). With the increased of age, the prevalence of thyroid nodules in male and female increased gradually(P＜0.05), and the prevalence of female was significantly higher in men≥60 years(P＜0.05). In male and female, the detection rates of nodules in the abnormal thyroid function group were significantly higher than in the normal thyroid function group, and the differences were statistically significant(P＜0.05). Logistic regression showed that age≥ 60 and smoking were risk factors for thyroid nodules. Conclusion The detection rate of thyroid nodules in women in Longnan region of Gansu is higher than that of men, and it gradually increases with age. Abnormal thyroid function may affect the occurrence of thyroid nodules