Dilated Cardiomyopathy With Left Ventricular Thrombi as a Presenting Feature of Cushing Disease |
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| Authors: | Ji Hye Kim So Young Kim Ji Hyun Park |
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| Affiliation: | 1. Department of Internal Medicine, Presbyterian Medical Center, Jeonju, Republic of Korea;2. Department of Internal Medicine, Gunsan Medical Center, Gunsan, Republic of Korea;3. Department of Internal Medicine, Chonbuk National University Medical School, Research Institute of Clinical Medicine, Jeonju, Republic of Korea |
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| Abstract: | We report on a 20-year-old man with dilated cardiomyopathy and intracardiac thrombi associated with Cushing disease (CD). The patient presented with symptomatic heart failure. Follow-up echocardiography showed 2 thrombi in the apex of the left ventricle, which resolved after intravenous heparin therapy. The patient was first treated symptomatically, and then trans-sphenoidal adenomectomy was performed. Although cortisol excess alone may not be sufficient to produce severe cardiomyopathy, progressive improvement of cardiac function was observed within 3 years after surgery. |
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