| Changes of Immunoreactive β-Endorphin in Plasma, Pituitary and Hypothalamus of Rats during Oxygen-Induced Convulsions |
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| 作者姓名： | 陶恒沂 倪国坛 |
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| 作者单位： | Department of Diving Physiology Faculty of Naval Medicine Second Military Medical University Shanghai，Department of Diving Physiology Faculty of Naval Medicine Second Military Medical University Shanghai |
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| 摘 要： | We observed for the first time the differences of immunoreactive β-endorphin(IR -β- EP) content in plasma, pituitary and hypothalamus of rats under various conditionsusing radioimmunoassay (RIA) and the effects of naloxone and β - endorphin (β- EP) antiserumon initial time of convulsions (ITC), severity of convulsions(SOC) and mortality on surface(MOS) of rats to hyperbaric oxygen(HBO). The results suggest thatβ- EP may partici-pate in the course of oxygen - induced convulsions and be one of endogenous convulsion - causingagents.
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| 关 键 词： | β-endorphin oxygen-induced convulsions naloxone radioimmunoassay antiserum rats |
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