持续床边血液净化治疗急性重型胰腺炎临床疗效分析

目的]探讨持续床边血液净化治疗急性重型胰腺炎的临床疗效。方法]选择某院2009年11月～2011年8月期间收治的急性重型胰腺炎患者72例,根据区组随机化分组方法将患者分为研究组和对照组,每组36例。对照组患者采用常规基础治疗,研究组患者在对照组基础上进行持续床边血液净化治疗。结果]与对照组相比,研究组患者的平均动脉压明显增高,而心率则明显降低,PCT、SCr、CRP、TB、ALT、AMS、APS等血清生化指标均显著改善,腹痛消失时间、腹胀缓解时间、住院时间均明显缩短,且并发症发生率明显降低,而临床治愈率则显著提高,差别均具有统计学意义(P﹤0.05)。结论持续床边血液净化能够有效的提高患者的抢救率,减少并发症的发生,对于提高急性重型胰腺炎患者的治愈效果具有重要的作用。

ANALYSIS OF CLINICAL EFFECTS OF CONTINUE BEDSIDE BLOOD PURIFICATION THERAPY FOR SEVERE ACUTE PANCREATITIS

Objective]To probe the clinical effect of continue bedside blood purification therapy for severe acute pancreatitis.Methods]Chose 72 patients with acute severe pancreatitis in our hospital from November 2009-August 2011.According to block randomization method,patients were divided into study group and control group,each of 36 cases.Two groups were treated with conventional treatment,on the basis of the conventional treatment,the study group was given blood purification treatment.Results]Compared with the control group,the mean arterial pressure in the study group was significantly higher and heart rate was significantly lower,PCT,SCr,CRP,TB,ALT,AMS,APS and other serum biochemical parameters were significantly improved,extinction time of abdominal pain,relief time of abdominal distention,hospitalization time were significantly shortened,and the complication rate was significantly reduced,while the clinical cure rate was significantly increased,there were statistically significant differences(P﹤0.05).Conclusion]Continue bedside blood purification can effectively improve the patient’s rescue rates,reduce complications,the effect has an important role for improving healing in patients with acute severe pancreatitis.