| 微囊化移植的研究进展 |
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| 引用本文： | 武林枫,翟博.微囊化移植的研究进展[J].国际生物医学工程杂志,2005,28(1):37-39. |
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| 作者姓名： | 武林枫 翟博 |
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| 作者单位： | 150001,哈尔滨医科大学附属第一临床医学院普外二科;150001,哈尔滨医科大学附属第一临床医学院普外二科 |
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| 基金项目： | 黑龙江省自然科学基金资助项目(D01-13) |
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| 摘 要： | 微囊移植技术能起有效的免疫隔离作用,为解决排斥反应、供体缺乏等问题提供了新思路。目前以海藻酸钠-多聚赖氨酸-海藻酸钠(APA)微囊发展最为成熟,但最近海藻酸-钡交联微囊也受到众多研究者的好评。微囊具有良好的免疫隔离作用,可使移植物较长时间存活,并维持良好功能。猪胰岛已经成为人们公认的良好供体。微囊移植虽尚不适于临床,但经不断完善必将在临床上有广泛的应用前景。
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| 关 键 词： | 微囊 移植 生物相容性 免疫隔离 |
| 文章编号： | 1001-1110(2005)01-0037-03 |
| 修稿时间： | 2004年6月5日 |
The progress in microencapsulated transplantation |
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| WU Lin-feng,ZHAI Bo.The progress in microencapsulated transplantation[J].International Journal of Biomedical Engineering,2005,28(1):37-39. |
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| Authors: | WU Lin-feng ZHAI Bo |
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| Abstract: | Microencapsulation transplantation is a useful approach to immunoisolation. It's a new method to solve the problem of donors shortage. Alginate-polylysine-alginate microencapsulation is the most successful microencapsulation, but microencapsulation which is made up of alginate crosslinked with BaCl2 without a traditional permselective component has been supported by many researchers. Microencapsulation can prolong the survival time of the transplanted cells. It is well known that porcine are the most suitable donors. Microencapsulation has not been clinically successfully, but the technique are improving. |
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| Keywords: | microencapsulation transplantation biocompatibility immunoisolation |
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