| 缺血预适应对兔在体心室肌室颤阈的影响 |
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| 引用本文： | 叶昕涛,蓝玉福,陈晓春.缺血预适应对兔在体心室肌室颤阈的影响[J].福建医科大学学报,2001,35(1):40-42. |
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| 作者姓名： | 叶昕涛 蓝玉福 陈晓春 |
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| 作者单位： | 福建医科大学附属协和医院干部病房,福建医科大学老年病学研究所, |
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| 摘 要： | 目的 探讨兔右冠脉缺血预适应（IP)对缺血再灌注心室肌室颤阈（VFT）的影响。方法 采用RS2程序电刺激法，测量缺血再灌注（IR）组（I30min R30min)及缺血预适应（IP）组（I5min＋R10min＋I30min＋R30min）在缺血30min内及再灌注30min内VFT的变化。结果 （1）IR组缺血心室肌VFT于I30mi、R30min内比IR组升高，差异有显著性（P＜0．01）。结论 IP可提高缺血及再灌注心室肌的室颤阈。
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| 关 键 词： | 缺血预适应 右冠状动脉 心室颤动 心肌缺血 家兔 |
| 文章编号： | 1000 2235(2001)01-0040-03 |
Effect of Ischemia preconditioning of Coronary Arteryon Threshold of Ventricular Fibrillation in Rabbit |
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| YE Xin tao,LAN Yu fu,CHEN Xiao chun.Effect of Ischemia preconditioning of Coronary Arteryon Threshold of Ventricular Fibrillation in Rabbit[J].Journal of Fujian Medical University,2001,35(1):40-42. |
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| Authors: | YE Xin tao LAN Yu fu CHEN Xiao chun |
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| Abstract: | Objective\ To investigate the effect of electrophysiological mechanism by which ischemia\|preconditioning(IP) in the right coronary artery of rabbit increases ventricular fibrillation threshold(VFT) during ischemia and reperfusion(IR).\ Methods\ The alterations of VFT in IP group(I 5 min+R10 min+I 30 min+R 30 min) or IR group(I 30 min+R 30 min) were examined during ischemia and after reperfusion by means of RS2 programed electrical stimulation(PES) according to the sequential single stimulus principle.\ Results\ The alterations of VFT in IP group and IR group during ischemia were lower than those after reperfusion(P<0 01). Compared with the IR group, IP markedly increased VFT during ischemia and after reperfusion(P<0 01).\ Conclusion\ IP could increase VFT induced by IR. |
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| Keywords: | ischemia preconditioning right coronary artery ventricular fibrillation mycardial \ischemia rat |
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