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炒制东北苍耳子Xanthium mongolicum化学成分研究
引用本文:白玉华,张秀花,于辉,韩成花,刘金成,于春月,康艳萍. 炒制东北苍耳子Xanthium mongolicum化学成分研究[J]. 中国医药导报, 2012, 9(1): 61-62
作者姓名:白玉华  张秀花  于辉  韩成花  刘金成  于春月  康艳萍
作者单位:哈尔滨医科大学大庆校区,黑龙江大庆,163319
基金项目:黑龙江省自然科学基金(留学归国人员及海外合作基金)(项目编号:LC2009C12)
摘    要:目的:研究炒制后东北苍耳子的化学成分。方法:利用超声波提取法及有机溶剂萃取对炒制东北苍耳子进行提取,开放柱色谱法、薄层色谱法对氯仿提取物进行分离和纯化,通过核磁共振波普学方法对分离到的化合物进行结构鉴定。结果:确定了4个化合物β-谷甾醇(Ⅰ)、豆甾醇(Ⅱ)、齐墩果酸(Ⅲ)和苍耳素(Ⅳ)。结论:这四个化合物为首次从炒制东北苍耳子中分离得。

关 键 词:东北苍耳子  炒制  化学成分

Study on chemical constituents of toasted Xanthium mongolicum in Northeast
BAI Yuhua,ZHANG Xiuhua,YU Hui,HAN Chenghua,LIU Jincheng,YU Chunyue,KANG Yanping. Study on chemical constituents of toasted Xanthium mongolicum in Northeast[J]. China Medical Herald, 2012, 9(1): 61-62
Authors:BAI Yuhua  ZHANG Xiuhua  YU Hui  HAN Chenghua  LIU Jincheng  YU Chunyue  KANG Yanping
Affiliation:Daqing Campus of Harbin Medical University,Heilongjiang Province,Daqing 163319,China
Abstract:Objective: To study the chemical constituents of toasted Xanthium mongolicum.Methods: Organic solvent extraction process coupled with ultrasonic extraction,column chromatographic techniques,thin layer chromatography were employed for the isolation and purification of its constituents,and structurally identified by spectral analysis(1HNMR,13CNMR) and chemical evidences.Results: Four compounds were identified from its chloroform extract as β-sitosterol(Ⅰ),stigmasterol(Ⅱ),Oleanolic acid(Ⅲ) and 11-α,13-dihydroxanthatin(Ⅳ).Conclusion: These compounds are reported from the toasted Xanthium mongolicum for the first time.
Keywords:Xanthium mongolicum in Northest  Toasted  Chemical constituents
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