高原汽车兵血清Hcy、叶酸和维生素B12的测定及相关性研究

目的 了解高原汽车兵血清同型半胱氨酸(Hcy)水平和营养状况,为合理补充营养提供依据.方法 采用S-腺苷酶法和酶促间接化学发光法,对36名在海拔3700 m以上高原生活9个月的汽车兵和40名在海拔1500 m平原生活的汽车兵进行了血清Hcy、叶酸和维生素B12含量的测定.结果 高原组血清Hcy含量明显高于平原组(P＜0.05),而血清叶酸和维生素B12的含量明显低于平原组(P＜0.05).结论 高原汽车兵血清Hcy明显偏高,营养不够合理,有必要进行营养干预.

Detection of Hcy,folic acid and vitamin B12 in blood serum of motor soldiers at high altitude and their correlation

Objective To understand the blood serum homocysteine（Hcy）level and nutritional status of motor soldiers at high altitude,and to provide evidence for supplement of nutrition.Methods Thirty six motor soldiers who lived at the altitude above 3,700 m for 9 months and 40 motor soldiers in the plain area were selected.Their serum Hcy,folic acid and vitamin B12 content were detected by the method of S-adenosinase and indirect enzymatic chemiluminescence.Results The blood serum Hcy content of the high altitude group was significantly higher than that of the plain group（P0.05）.But the serum folic acid and vitamin B12 were significantly lower than those of the plain group（P0.05）.Conclusion The serum Hcy of the motor soldiers at high altitude is significantly high,and the nutritional status of them is unreasonable.Active nutrition intervention is necessary.