About human tumor antigens to be used in immunotherapy |
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Authors: | Lucas S Coulie P G |
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Affiliation: | de Duve Institute and Université catholique de Louvain, B-1200 Brussels, Belgium. sophie.lucas@uclouvain.be |
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Abstract: | The choice of antigens to be used in cancer immunotherapy remains a crucial and difficult issue. This review highlights some properties of the different groups of human tumor antigens recognized by T lymphocytes, focusing on parameters that should influence this choice, such as tumor specificity and level of antigen expression. |
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