| 重组人脑利钠肽治疗心血管疾病研究进展 |
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| 引用本文： | 李文安. 重组人脑利钠肽治疗心血管疾病研究进展[J]. 心血管病学进展, 2010, 31(4): 606-608. DOI: 10.3969/j.issn.1004-3934.2010.04.033 |
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| 作者姓名： | 李文安 |
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| 作者单位： | 中南大学湘雅二医院老年科,湖南,长沙,410011 |
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| 摘 要： | 重组人脑利钠肽是模拟内源性B型钠尿肽发挥生理作用的。近年的研究证实,重组人脑利钠肽治疗成人急性心力衰竭是安全、有效、耐受性好的;静脉注射重组人脑利钠肽能迅速降低急性心力衰竭患者的肺毛细血管楔压,缓解呼吸困难症状,改善预后。研究发现,重组人脑利钠肽还能减轻心肌梗死后心室重构,减轻婴儿和儿童心力衰竭,降低肺动脉高压,缓解心脏移植等待期患儿的病情。
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| 关 键 词： | 重组人脑利钠肽 心力衰竭 肺动脉高压 心血管病 |
Progress of Recombinant Human B-type Natriuretic Peptide in Treating Heart and Vascular Diseases |
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| LI Wen-an. Progress of Recombinant Human B-type Natriuretic Peptide in Treating Heart and Vascular Diseases[J]. Advances in Cardiovascular Diseases, 2010, 31(4): 606-608. DOI: 10.3969/j.issn.1004-3934.2010.04.033 |
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| Authors: | LI Wen-an |
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| Affiliation: | LI Wen-an,YANG Yu(Department of Geriatrics,The Second Xiangya Hospital of Central South University,Changsha 410011,China) |
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| Abstract: | The recombinant human B-type natriuretic peptide produces physiological effects by imitating endogenous B-type natriuretic peptide.According to recent research,the recombinant human B-type natriuretic peptide is safe and effective in treating acute heart failure.Intravenous recombinant human B-type natriuretic peptide can quickly degrade pulmonary capillary wedge pressure,relieve dyspnea,and improve a patient＇s prognosis.Some research has found that the recombinant human B-type natriuretic peptide can also degrade ventricular remodeling that occurs after myocardial infarct,relieve heart failure symptoms in infants and children,and degrade pulmonary artery hypertension. |
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| Keywords: | recombinant human B-type natriuretic peptide heart failure pulmonary artery hypertension cardiovascular diseases |
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