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iNOS在大鼠性成熟期睾丸组织的表达变化及意义
引用本文:任亚萍,孙莉,毛庭枝,邵晓云,陈筠,农林琳.iNOS在大鼠性成熟期睾丸组织的表达变化及意义[J].华夏医学,2009,22(5):841-843.
作者姓名:任亚萍  孙莉  毛庭枝  邵晓云  陈筠  农林琳
作者单位:桂林医学院组胚教研室,广西桂林,541004
摘    要:目的:探讨诱导型一氧化氮合酶(iNOS)在雄性SD大鼠性成熟期睾丸中的表达变化情况及意义。方法:选取出生后5周、7周和10周的雄性SD大鼠各6只,左侧睾丸行石蜡切片,运用免疫组化ABC法观察iNOS在雄性SD大鼠性成熟期睾丸中的表达变化情况。结果:1出生后5周,iNOS睾丸间质细胞阴性表达。2出生后7周,绝大部分生精小管断面有精子发生,iNOS睾丸间质细胞弱阳性表达,精母细胞阳性表达。3出生后10周,iNOS睾丸间质细胞强阳性表达,精母细胞阳性表达。结论:在雄性SD大鼠的睾丸间质细胞中,随着性成熟发育iNOS的表达渐强。

关 键 词:一氧化氮合酶  睾丸  大鼠  性成熟

The expression and significance of the iNOS in the sexual-maturity SD rat's testis
REN Ya-ping,SHUN Li,MAO Tin-zhi,et al..The expression and significance of the iNOS in the sexual-maturity SD rat's testis[J].Acta Medicinae Sinica,2009,22(5):841-843.
Authors:REN Ya-ping  SHUN Li  MAO Tin-zhi  
Institution:REN Ya-ping,SHUN Li,MAO Tin-zhi,et al.Depatment of Histology and Embryology,Guilin Medical College,Guilin 541004,China
Abstract:Objective:To explore the expression and significance of the inducible nitric oxide synthase(iNOS) in the sexual-maturity male SD rat's testis.Methods: Eighteen male SD rats born for 5 weeks,7 weeks and 10 weeks were selected with each 6 rats.Paraffin sections of the left testis were made and the expression of the iNOS in the testis of male SD rat was observed by immunohistochemical ABC method.Results: iNOS was expressed in Leydig cells of the testis,and the positive degree were(-),(++) and(+++) respectively...
Keywords:iNOS  testis  SD rat  sexual maturity  
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