住院患者多药耐药菌感染的监测分析

目的 调查住院患者多药耐药菌感染的情况,为预防控制医院感染提供依据.方法 对2009年1月-2010年12月检出的耐甲氧西林金黄色葡萄球菌(MRSA)、耐万古霉素肠球菌(VRE)、耐碳青霉烯类铜绿假单胞菌和泛耐药鲍氏不动杆菌进行统计分析.结果 多药耐药菌感染部位以呼吸系统为主,占73.1％；神经外科、ICU多药耐药菌感染较严重,分别占总感染数的30.0％、27.0％；MRSA、泛耐药鲍氏不动杆菌,已成为医院多药耐药菌感染的主要致病菌.结论 加强对多药耐药菌的监测,合理使用抗菌药物,做好消毒隔离及手卫生,可有效防止耐药菌株的流行和传播.

Monitoring and analysis of multiple drug-resistant infections in inpatients

OBJECTIVE To investigate patients with multiple drug-resistant hospital infections,in order to provide evidence for prevention and control of hospital infection.METHODS All of the methicillin-resistant Staphylococcus aureus(MRSA),vancomycin-resistant Enterococcus(VRE),carbapenem-resistant Pseudomonas aeruginosa and Acinetobacter baumannii strains detected from Jan.2009 to Dec.2010 were statistically analyzed.RESULTS The main infection site was the respiratory system,accounting for 73.1%;the multiple drug-resistant infections were relatively more severe in the department of Neurosurgery and ICU,30.0% and 27.0% respectively.MRSA and pan-resistant Acinetobacter bacteria were the major pathogens of the multi-drug resistant infections.CONCLUSION Stronger monitoring of multi-drug resistant pathogens,rational use of antimicrobial drugs,disinfection,isolation and good hand hygiene can prevent the prevalence and spread of resistant strains.