Histochemical analyses of glycoconjugates and antimicrobial substances in goat labial glands |
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Authors: | Habata Isao Yasui Tadashi Fujimori Osamu Meyer Wilfried Tsukise Azuma |
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Affiliation: | a Department of Veterinary Anatomy, College of Bioresource Sciences, Nihon University, 1866 Kameino, Fujisawa, Kanagawa 252-0880, Japan b Laboratory of Anatomy and Histochemistry, Faculty of Rehabilitation Science, Nagoya Gakuin University, 1350 Kamishinanocho, Seto, Aichi 480-1298, Japan c Institute for Anatomy, University of Veterinary Medicine Hannover Foundation, Bischofsholer Damm 15, D-30173 Hannover, Germany |
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Abstract: | Saliva is known to protect the oral cavity and contains glycoproteins and antimicrobial substances. The distribution of these salivary secretions was studied in the labial glands of the Japanese miniature (Shiba) goat using lectin histochemical and immunohistochemical methods. The mucous acinar cells of the labial glands exhibited glycoconjugates with different saccharide residues, such as GalNAcα1-3GalNAc, Galβ1-4GalNAc, β-d-GlcNAc and sialic acid linked to α2-6Gal/GalNAc. Furthermore, α-d-Man, α-l-Fuc, α-d-GalNAc, β-d-Gal and sialic acid residues were present, in particular, in the serous demilunar cells. Antimicrobial substances (lysozyme, IgA, lactoferrin and β-defensin) were shown to be mainly immunolocalized in the serous demilunes and duct cells. The results obtained are discussed with regard to the functional role of labial glands. The secretory compounds demonstrated may play an important role in the maintenance of oral health with regard to saliva. |
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Keywords: | Labial glands Glycoconjugates Antimicrobial substances Histochemistry Goat |
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