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Establishment of a biorepository for migraine research: the experience of Interinstitutional Multidisciplinary BioBank (BioBIM)
Authors:Raffaele Palmirotta  Piero Barbanti  Giorgia Ludovici  Gabriella Egeo  Cinzia Aurilia  Luisa Fofi  Maria Laura De Marchis  Antonella Spila  Patrizia Ferroni  David Della-Morte  Fiorella Guadagni
Affiliation:1. Interinstitutional Multidisciplinary BioBank (BioBIM), Department of Laboratory Medicine and Advanced Biotechnologies, IRCCS San Raffaele Pisana, Via Della Pisana 235, 00163, Rome, Italy
2. Headache and Pain Unit, Department of Neurological, Motor and Sensorial Sciences, IRCCS San Raffaele Pisana, Via Della Pisana 235, 00163, Rome, Italy
3. Department of Neurology, Miller School of Medicine, University of Miami, Miami, FL, 33136, USA
Abstract:The development of Biobanks and recent advances in molecular biology have enhanced the possibility to accelerate translational research studies. The Interinstitutional Multidisciplinary BioBank (BioBIM) is organized in a large healthy donors collection and pathology-based biobanks with the aim to provide a service for development of interdisciplinary studies. A new pathology-based biobank has been organized to specifically collect biospecimen from patients affected by migraine, with the final goal to centralize data, collect blood, plasma, serum, DNA and RNA of patients with this disease. The BioBIM is fully equipped for the automation of sampling/processing, storage and tracking of biospecimens. Standard Operating Procedures have been developed for processing and storage phases as well as archive of clinical data. The availability of biospecimens and clinical data will constitute a resource for various research projects.
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