婴儿隐孢子虫肠炎4例临床特点及九年后随访

目的：介绍隐孢子虫感染4例婴儿肠炎的临床特点及9年后随访的情况，探讨该病的有效防治措施。方法：取患婴和家人以及所饲养的牲畜的新鲜粪便，用改良抗酸染色法涂片标本检查；并通过动物（鼠）模型的实验以确诊。结果：在随机抽样的271例4岁以下腹泻婴幼儿住院中，确诊4例患儿患隐孢子虫肠炎。检出率1.47%（4／27）。经用大蒜素治愈出院。9年后随访，患儿和其家人以及饲养牲畜之粪便检查，均呈阴性。结论：隐孢子虫肠炎是人畜共患的寄生虫病，好发于夏季，多见于营养不良的小婴儿。患婴以腹泻为主，可伴发呼吸道疾患。大蒜素治疗效果显，无副作用。婴儿感染与喂养方式（母乳或人工）相关性不明显，而与卫生环境，水源的污染密切相关。注意卫生与改善环境条件以及提高饮用、洗盥水的质量，可有效地预防本病。

Clinical Features of 4 Cases of Infant Cryptosporidium Enteritis

Objective:4 cases of infant Cryptosporidium entenitis were reported. Method: Fecal samples form 271 infants with diarrhea under 4 years old and their parents and the domestic animals were examined for cryptosporidium by the modified acid-fast staining. Animal models were used to confirmed the results. Result: 4 infants were diagnosed as cryptosporidium enteritis,with the positive rate of 1.47%. Diarrhea was the main clinical manifestation accompanied with respiratory disorders. The sick infants were cured by the use of garcilin. Fecal examinations were negative 9 years after the treatment. Conclusion: Cryptosporidium enteritis is a kind of zoonosis,mainly found in malnutritional infants. Garcilin is effective in the treatment of this disease.