Secretor status, candidal carriage and candidal infection in patients with diabetes mellitus |
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| Authors: | P.-J. Lamey A. Darwaza B. M. Fisher L. P. Samaranayake T. W. Macfarlane B. M. Frier |
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| Affiliation: | Department of Oral Medicine and Pathology, Glasgow Dental Hospital and School, Glasgow, Scotland.;Diabetic Clinic, Gartnavel General Hospital, Glasgow, Scotland. |
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| Abstract: | One hundred and nine patients with diabetes mellitus and 100 age-, sex- and denture-status-matched, non-diabetic individuals were investigated prospectively. Comparison was made of oral candidal carriage, clinical infection and inherited ability to secrete blood group antigens in saliva. Diabetic patients had a significantly higher prevalence of oral candidal carriage and infection (P < 0.001) than non-diabetic individuals, but the candidal load between the 2 groups, was not significant. A comparable proportion of insulin-dependent, non-insulin dependent and control groups were secretors of blood group antigens, and there was no difference in the oral candidal carriage and infection rates between secretors and non-secretors. |
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