Imaging findings in patients with myelofibrosis |
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Authors: | A. Guermazi E. de Kerviler D. Cazals-Hatem A.-M. Zagdanski J. Frija |
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Affiliation: | (1) Department of Radiology, Saint-Louis Hospital, 1 avenue Claude Vellefaux, F-75010 Paris, France, FR;(2) Department of Cytopathology, Saint-Louis Hospital, 1 avenue Claude Vellefaux, F-75010 Paris, France, FR |
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Abstract: | The purpose of this review is to illustrate the wide range of radiological abnormalities in myelofibrosis. Myelofibrosis, also called myeloid metaplasia, is a myeloproliferative disorder of unknown etiology. The common imaging findings in patients with myelofibrosis are osteosclerosis, hepatosplenomegaly, and lymphadenopathies. In addition, extramedullary hematopoiesis may develop in multiple sites such as chest, abdomen, pelvis, and central nervous system, simulating malignant disease. Selected plain-film, CT, and MR images in patients with myelofibrosis are shown as pictorial essay to allow ready recognition of the most common imaging abnormalities of the disease. Received: 6 August 1998; Revision received: 15 October 1998; Accepted: 20 November 1998 |
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Keywords: | : Myelofibrosis Plain film Ultrasound CT MR imaging Extramedullary hematopoiesis |
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