102例系统性红斑狼疮肝损害患者特点及危险因素分析

目的:了解系统性红斑狼疮肝脏受累的特点,为临床诊断、鉴别诊断提供依据。方法:回顾性分析系统性红斑狼疮患者566例,比较狼疮性肝损害与无肝损害患者的一般情况、实验室检查结果及预后,并对狼疮性肝损害发生的危险因素进行分析。结果:566例系统性红斑狼疮患者中,狼疮性肝损害患者102例(18.02%)。狼疮性肝损害患者与无肝损害患者相比IgG较高[(18.65±8.64)g/L比(15.80±7.14)g/L,P<0.05],系统性红斑狼疮疾病活动指数(SLEDAI)较高(13.3±8.4比11.3±6.5,P<0.05),病程较短[(3.0±4.6)年比(4.2±6.0)年,P

Analysis of clinical features and risk factors of 102 cases of lupus-associated hepatitis

Objective To study the clinical features of liver involvement in systemic lupus erythematosus(SLE) for providing reliable clue for clinical diagnosis and differential diagnosis. Methods Retrospective analysis was performed in 566 cases of SLE in-patients. Lupus-associated hepatitis patients and SLE patients without liver disorder were compared in term of : general condition, laboratory findings and prognosis. The risk factors of lupus-associated hepatitis were analyzed. Suspected risk factors were selected ...