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复方甘草酸苷联合人工肝治疗重型肝炎疗效观察
引用本文:刘春华,吴玮.复方甘草酸苷联合人工肝治疗重型肝炎疗效观察[J].中国药房,2005,16(16):1248-1249.
作者姓名:刘春华  吴玮
作者单位:山东青岛市传染病医院,青岛市,266033
摘    要:目的:观察复方甘草酸苷联合人工肝治疗重型肝炎的疗效。方法:将58例重型肝炎患者随机分为治疗组和对照组,对照组除给予基础治疗外,根据患者情况每隔3d~5d行血浆置换或血液灌流,每位患者一般做5次~10次;治疗组在对照组治疗的基础上给予复方甘草酸苷治疗。结果:治疗组与对照组总有效率分别为64.52%、40.74%,二者间有显著性差异(P<0.05);治疗8wk时治疗组肝功能改善情况优于对照组(P<0.05)。结论:复方甘草酸苷联合人工肝治疗重型肝炎有效、安全。

关 键 词:复方甘草酸苷  人工肝  重型肝炎  疗效
文章编号:1001-0408(2005)16-1248-02
收稿时间:2004-08-30
修稿时间:2004年8月30日

Observation of Therapeutic Effect of Compound Glycyrrhizin Combining Artificial Liver on Severe Hepatitis
Liu Chunhua,WU Wei.Observation of Therapeutic Effect of Compound Glycyrrhizin Combining Artificial Liver on Severe Hepatitis[J].China Pharmacy,2005,16(16):1248-1249.
Authors:Liu Chunhua  WU Wei
Abstract:OBJECTIVE:To investigate the effect of compound glycyrrhizin(SNMC)combining artificial liver on severe hepatitis.METHODS:58patients with severe hepatitis were randomly divided into two groups,for the control group,apart from the basic treatment,each of them was also given plasmapheresis or hemoperfusion every3d~5d for5~10times acˉcording to their state of illness;For the treatment group,they were treated with SNMC apart from the therapy of the control group.RESULTS:The total effective rates of the treatment group and the control group were64.52%and40.74%,respecˉtively,thus significant differences existed between the2groups(P<0.05);The hepatic function of the treatment group had a greater improvement than the control group after receiving treatment for8weeks(P<0.05).CONCLUSION:SNMC combining artificial liver is effective and safe in the treatment of severe hepatitis.
Keywords:Compound glycyrrhizin  Artificial Liver  Severe hepatitis  Therapeutical effect
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