Fetal response to intramuscular epinephrine for anaphylaxis during maternal penicillin desensitization for secondary syphilis |
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| Authors: | Shan Shan Wu Tina Abraham Chelsea Michaud Brian Peppers Andrea Ward Stacey Ehrenberg Buchner |
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| Affiliation: | 1. Internal Medicine Residency Program, University Hospitals Regional Hospitals, Richmond Heights, OH, USA;2. Allergy/Immunology Fellowship Program, University Hospitals Cleveland Medical Center, Cleveland, OH, USA;3. Obstetrics and Gynecology Residency Program, University Hospitals Cleveland Medical Center, Cleveland, OH, USA;4. Department of Obstetrics and Gynecology, University Hospitals Cleveland Medical Center, Cleveland, OH, USA |
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| Abstract: | Penicillin desensitization is indicated in pregnant patients with severe allergies to penicillin with syphilis. The immediate effects of intramuscular epinephrine on the fetus during desensitization remain unreported. We describe a pregnant patient with secondary syphilis and penicillin allergy who developed anaphylaxis during penicillin desensitization. Anaphylaxis resolved after administration of intramuscular epinephrine. Throughout the procedure, continuous electronic fetal monitoring showed a stable fetus without a decrease in variability, tachycardia, decelerations, or signs of fetal distress. This case showed that intramuscular epinephrine is effective in treatment of anaphylaxis in a pregnant patient with little to no immediate effects on the fetus. |
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| Keywords: | Epinephrine desensitization anaphylaxis fetus syphilis |
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