| 硝苯地平、乙酰水杨酸对培养大鼠心肌细胞~(45)Ca摄取的影响 |
| |
| 引用本文： | 董尔丹,石山. 硝苯地平、乙酰水杨酸对培养大鼠心肌细胞~(45)Ca摄取的影响[J]. 中国循环杂志, 1993, 0(5) |
| |
| 作者姓名： | 董尔丹 石山 |
| |
| 作者单位： | 北京医科大学第三医院心血管研究所(董尔丹)，包头医学院心血管研究室(石山) |
| |
| 摘 要： | 硝苯地平(硝苯吡啶)抑制大鼠心肌细胞对~(45)Ca的摄取,表现为钙拮抗作用,且呈良好的量效关系。乙酰水杨酸(阿司匹林)也有钙拮抗倾向,大剂量明显抑制~(45)Ca的摄取,两药合用有协同作用。
|
| 关 键 词： | 硝苯地平 乙酰水杨酸 氯化镧 ~(45)Ca摄取 大鼠 心肌细胞 |
EFFECTS OF NIFEDIPINE,ASPIRIN ON ~(45)Ca UPTAKE BY CULTURED RAT HEART CELLS |
| |
| Dong Er-Dan,Shi Shan. Laboratory of Cardiovascular Research,Baotou Medical College,Baotou. EFFECTS OF NIFEDIPINE,ASPIRIN ON ~(45)Ca UPTAKE BY CULTURED RAT HEART CELLS[J]. Chinese Circulation Journal, 1993, 0(5) |
| |
| Authors: | Dong Er-Dan Shi Shan. Laboratory of Cardiovascular Research Baotou Medical College Baotou |
| |
| Abstract: | The effects of nifedipine (Nif), aspirin (ASA) and Nif ASA on (45)~Ca uptake by cultured rat heart cells were studied. The results showed that Nif inhibited the rate of (45)~Ca uptake by cultured rat heart cells and the inhibition was dose-dependent. ASA seemed to be antagonistic to (45)~Ca. Heavy dose (5.lmM) of ASA had significant inhibitory effect on the uptake of (45)~Ca and Nif ASA showed increased effect than either Nif or ASA. |
| |
| Keywords: | Nifedipine Aspirin LaCl_3 ~(45)Ca uptake Rat heart cell |
| 本文献已被 CNKI 等数据库收录！ |
