阿托伐他汀联合非诺贝特治疗急性冠状动脉综合征的临床疗效及安全性探讨

目的探讨阿托伐他汀联合非诺贝特治疗急性冠状动脉综合征的临床疗效及安全性。方法选择我院心内科收治的90例急性冠状动脉综合征患者的资料,按照治疗方式分为观察组及对照组,对照组采用单药阿托伐他汀治疗,观察组在对照组基础上加用阿托伐他汀,连续治疗1年,比较两组患者血脂变化及心脑血管事件发生情况。结果观察组患者血脂指标改善明显,心血管不良事件发生率低,与对照组患者比较差异有统计学意义(P<0.05)。结论阿托伐他汀联合非诺贝特治疗急性冠状动脉综合征的临床疗效显著,两药合用有协同性,具有良好的安全性。

Atorvastatin Clinical Efficacy and Safety Explore Statin plus Fenofibrate Treatment of Acute Coronary Syndrome

Objective To investigate the atorvastatin statin plus fenofibrate clinical efficacy and safety in the treatment of acute coronary syndrome. Methods Hospital Cardiology, treated 90 patients with acute coronary syndrome, treatment is divided into observation group and control group, the control group using a single drug atorvastatin statin treatment, the observation group on the basis of the control group plus atorvastatin, one year of continuous treatment, the two groups were compared lipid changes and cardiovascular events. Results Observation group were significantly improved lipid parameters, a low incidence of adverse cardiovascular events compared with the control group of patients was statistically significant （P〈0.05） difference. Conclusion Atorvastatin statin plus fenofibrate significant clinical efficacy for the treatment of acute coronary syndrome, the two drugs have a synergistic, with good security.