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诺通鼻喷雾剂治疗慢性鼻炎的临床疗效观察
引用本文:谭华章,杨静,吴媛媛.诺通鼻喷雾剂治疗慢性鼻炎的临床疗效观察[J].中外医疗,2012,31(27):122+124-122,124.
作者姓名:谭华章  杨静  吴媛媛
作者单位:武汉大学基础医学院药理系,湖北武汉,430071
摘    要:目的观察诺通鼻喷剂在治疗慢性鼻炎中消除或缓解鼻塞症状的效果,探寻治疗慢性鼻炎的有效药物。方法慢性单纯性鼻炎、肥厚性鼻炎患者共100例,分别用诺通鼻喷剂(诺通组)和1%麻黄素滴鼻剂(麻黄素组)进行治疗,对比疗效。结果诺通组总有效率为90.8%,麻黄素组为74.3%。诺通组69.2%起效时间在1min以内,66.2%维持时间在5h以上;麻黄素组68.6%起效时间在3min以内,65.7%维持时间在3h以内。结论诺通鼻喷剂缓解鼻塞迅速,维持时间长,疗效显著,明显优于1%麻黄素滴鼻剂,是一种治疗慢性鼻炎的有效药物。

关 键 词:诺通鼻喷剂  1%麻黄素滴鼻剂  盐酸赛洛唑啉  慢性鼻炎

The clinical effect of NuoTong nasal spray on treating chronic rhinitis
TAN Huazhang , YANG Jing , WU Yuanyuan.The clinical effect of NuoTong nasal spray on treating chronic rhinitis[J].China Foreign Medical Treatment,2012,31(27):122+124-122,124.
Authors:TAN Huazhang  YANG Jing  WU Yuanyuan
Institution:Department of Pharmacology,the Basic Medical College of Wuhan University,Hubei Province,Wuhan 430071,China
Abstract:Objective To observe the effect of NuoTong nasal spray on decongesting rhinocleisis and to search effective drugs for treating chronic rhinitis.Methods 100 patients collected form chronic simple rhinitis and hypertrophic rhinitis were treated with NuoTong nasal spray(NuoTong group) or 1%Ephedrine nasal drops(Ephedrine group).Results The total efficiency of NuoTong group in treating chronic rhinitis above is 90.8% and that of Ephedrine group is 74.3%.The effective time of NuoTong group is 69.2% in 1 minute;and for Ephedrine group is 68.6% between 1 to 3 minutes.The keeping curative effect time for NuoTong nasal spray is 66.2% above 5 hours and for Ephedrine drops is 65.7% in 3 hours.Conclusion NuoTong nasal spray is better than 1% Ephedrine nasal drops in decongesting rhinocleisis,keeping curative effect.So NuoTong nasal spray is one kind of effective drugs in treating chronic rhinitis.
Keywords:NuoTong nasal spray  1%Ephedrine nasal drops  Xylometazoline hydrochloride  Chronic rhinitis
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