| 髓鞘碱性蛋白在肺腺癌A549细胞表达及其功能意义 |
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| 引用本文： | 袁兵,谭燕,王盛兰,赵珊,王殿华,张云辉. 髓鞘碱性蛋白在肺腺癌A549细胞表达及其功能意义[J]. 昆明医学院学报, 2011, 32(7): 52-54 |
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| 作者姓名： | 袁兵 谭燕 王盛兰 赵珊 王殿华 张云辉 |
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| 作者单位： | 1. 昆明医学院附属昆华医院·云南省第一人民医院呼吸内科,云南昆明650032
2. 昆明医学院云南省天然药物药理重点实验室,云南昆明,650031 |
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| 摘 要： | 目的研究髓鞘碱性蛋白（MBP）在肺腺癌A549细胞中的表达及意义.方法用含10%胎牛血清的RPMI Medium1640培养基培养肺腺癌A549细胞,免疫组化SP法检测MBP在肺腺癌A549细胞的表达情况,探讨其功能意义.结果 MBP在A549细胞中的表达,以新生细胞为主,胞浆染色,阳性率约为21.1%.结论 MBP部分在肺腺癌A549细胞表达,这些新生细胞表达MBP形态可能与肺癌细胞的增殖能力或肺癌的嗜神经特性有关.
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| 关 键 词： | MBP A549 肺癌 |
Functional Implication and Expression of MBP in Lung Adenocarcinoma Cells A549 |
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| YUAN Bing,TAN Yan,WANG Sheng-lan,ZHAO Shan,WANG Dian-hua,ZHANG Yun-hui. Functional Implication and Expression of MBP in Lung Adenocarcinoma Cells A549[J]. Journal of Kunming Medical College, 2011, 32(7): 52-54 |
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| Authors: | YUAN Bing TAN Yan WANG Sheng-lan ZHAO Shan WANG Dian-hua ZHANG Yun-hui |
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| Affiliation: | YUAN Bing1),TAN Yan1),WANG Sheng-lan1),ZHAO Shan1),WANG Dian-hua2),ZHANG Yun-hui1)(1)Dept.of Resparation,The First Affiliated Hospital of Yunnan Province,Kunming Medical College,Kunming Yunnan 650032,2)Yunnan Key Laboratory of Pharmacology for Natural Products,Kunming Medical University,Kunming Yunnan 650031,China) |
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| Abstract: | Objective To investigate the expression and its significance of myelin basic protein(MBP) in lung adenocarcinoma cells A549.Methods RPMI Medium 1640 with 10% fetal calf serum was used to culture lung adenocarcinoma cells A549,then the expression of MBP in lung adenocarcinoma cells A549 was detected by immunohistochemistry SP.Results Expression of MBP was mainly located in cytoplasm of lung adenocarcinoma cells A549,which exhibited a round shape,possibly as new cells.The positive rate of MBP positive cells w... |
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| Keywords: | MBP A549 Lung Cancer |
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