| BDNF在树鼩中枢神经系统的表达 |
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| 引用本文： | 何保丽,刘汝文,陈丽玲,李波,李进涛,角建林. BDNF在树鼩中枢神经系统的表达[J]. 昆明医学院学报, 2011, 32(9): 21-23 |
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| 作者姓名： | 何保丽 刘汝文 陈丽玲 李波 李进涛 角建林 |
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| 作者单位： | 昆明医学院实验动物中心,云南昆明,650201 |
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| 基金项目： | 国家科技支撑计划基金资助项目(2009BAI83B02); 云南省科技计划基金资助项目(2006PT07-01) |
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| 摘 要： | 目的观测脑源性神经营养因子（6rain-derived neurotrophic factor,BDNF）在树鼩中枢神经系统的表达.方法用RT—PCR技术探讨从胎儿、新生到成年过程中,观察树鼩中枢神经系统海马和脑干BDNF的表达变化.结果 BDNF在胎儿、新生和成年树鼩的海马和脑干均有表达,成年树鼩海马中的表达量显著高于胎儿和新生树鼩,差异有统计学意义（P〈0.05）.结论 BDNF在成年树鼩仍有较高的表达量.
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| 关 键 词： | 树鼩 脑源性神经营养因子 RT-PCR |
BDNF Expression in the Central Nervous System of Tree Shrews(Tupaia Belangeri Chinensis) |
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| HE Bao-li,LIU Ru-wen,CHEN Li-lin,LI Bo,LI Jin-tao,JIAO Jian-lin. BDNF Expression in the Central Nervous System of Tree Shrews(Tupaia Belangeri Chinensis)[J]. Journal of Kunming Medical College, 2011, 32(9): 21-23 |
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| Authors: | HE Bao-li LIU Ru-wen CHEN Li-lin LI Bo LI Jin-tao JIAO Jian-lin |
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| Affiliation: | HE Bao-li,LIU Ru-wen,CHEN Li-lin,LI Bo,LI Jin-tao,JIAO Jian-lin(Laboratory Animal Center,Kunming Medical University,Kunming Yunnan 650201,China) |
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| Abstract: | Objective To detect BDNF expression in the central nervous system(hippocampus and brainstem) of tree shrews.Method RT-PCR was used to detect BDNF expression in the central nervous system(hippocampus and brainstem) of tree shrews from embryo to adult.Results BDNF expressed in hippocampus and brainstem of tree shrews from embryo to adult.The expression level of BDNF mRNA in adult was significantly higher than that of embryo and newborn tree shrews(P<0.05).Conclusion The expression level of BDNF is still high ... |
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| Keywords: | Tree shrew BDNF RT-PCR |
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