BiPAP联合振动排痰治疗AECOPD合并呼吸衰竭的效果评价

目的探讨无创双水平气道正压通气联合振动排痰治疗慢性阻塞性肺疾病合并呼吸衰竭的临床效果。方法将40例患者随机分为A组与B组各20例。A组患者采用无创双水平正压通气联合振动排痰进行治疗，B组患者仅使用无创双水平正压通气治疗，观察两组的治疗效果。结果A组患者的PaCO2较B组下降快（P〈0．05），呼吸支持时间及住院时间亦明显缩短（P〈0．05），气管插管率较B组低（P〈0．05）。结论无创正压通气联合振动排痰对治疗慢性阻塞性肺疾病合并呼衰的患者具有明显优势，值得临床推广。

Effect of Bi-level positive airway pressure combined with vibration sputum elimination in the treatment of chronic obstructive pulmonary disease with acute exacerbation complicated with respiratory failure

Objective To evaluate the efficacy of Bi-level positive airway pressure （BiPAP） combined with vibration sputum elimination in the treatment of chronic obstructive pulmonary disease with acute exacerbation （AECOPD） complicated with respiratory failure. Methods 40 cases of patients with respiratory failure were randomly divided into group A （20 cases） and group B （20 cases）.The patients in group A were received noninvasive BiPAP ventilation and vibration sputum elimination.The patients in group B were treated with BiPAP ventilation only.Clinical effect in two groups were observed. Results After treatment,PaCO2 changed more significantly in group A than that in group B .The patients in group A had a significantly shorter duration of respiratory support than group B （P〈0.05）.The respiratory support time and hospital stay of group A was shorter than that of group B （P〈0.05）.The rate of endotracheal intubation of group A was lower than that of group B （P〈0.05）. Conclusion BiPAP combined with vibration sputum elimination in treatment of AECOPD complicated with respiratory failure has good curative effect and it is worth promoting.